المعاهدة التجارية بين البندقية وإمبراطورية نيقية البيزنطية عام 1219 م.

Dmd057190 1219..1226

Inhibition of bile acid transport by troglitazone (TGZ) and its major metabolite, TGZ sulfate (TS), may lead to hepatocellular accumulation of toxic bile acids; TS accumulation and hepatotoxicity may be associated with impaired TS biliary excretion. This study evaluated the impact of impaired transport of breast cancer resistance protein (Bcrp) and multidrug resistance–associated protein 2 (Mrp...

Dmd050666 1211..1219

Absorption, distribution, metabolism, and excretion properties of two unformulated model short interfering RNA (siRNAs) were determined using a single internal [H]-radiolabeling procedure, in which the full-length oligonucleotides were radiolabeled by Br/H -exchange. Tissue distribution, excretion, and mass balance of radioactivity were investigated in male CD-1 mice after a single intravenous ...

Npgrj_nn_1513 1210..1219

We sought to determine the neural code(s) for frequency discrimination of vibrotactile stimuli. We tested five possible candidate codes by analyzing the responses of single neurons recorded in primary somatosensory cortex of trained monkeys while they discriminated between two consecutive vibrotactile stimuli. Differences in the frequency of two stimuli could be discriminated using information ...

Npgrj_nm_1630 1219..1227

The repair of injured tendons remains a great challenge, largely owing to a lack of in-depth characterization of tendon cells and their precursors. We show that human and mouse tendons harbor a unique cell population, termed tendon stem/progenitor cells (TSPCs), that has universal stem cell characteristics such as clonogenicity, multipotency and self-renewal capacity. The isolated TSPCs could r...

NSMRL TECHNICAL REPORT #1219 26 NOVEMBER 2001 The Medical Implications of Women On Submarines